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Imiquimod, sold under the brand names Aldara and Zyclara, is a medication used for topical treatment of various skin conditions, including genital warts. Use the medicine before going to bed and leave it on for 8 hours. The active substance in Aldara cream, imiquimod, is an immune-response modifier. This is a common slow-growing form of skin cancer with a very small likelihood of spread to other parts of the body Aldara safely and effectively. Wash your hands after applying the cream. Apply the cream to the treatment area in a thin layer, and rub in the cream until it disappears. We offer a next-day discreet delivery on orders approved by our doctors before 3pm, weekdays Aldara (imiquimod) is a prescription topical cream that works as an immunomodulator. -when starting the treatment, only apply a really tiny amount of cream on each wart with the end of a cotton bud. The males for whom case reports were submitted were 1. Use a new packet of cream for each use. 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